Lo and Li were Azula's two elderly advisers. They were cold, focused people who contributed to Azula's undeniable thirst for power. Although not firebenders themselves, they served as mentors for Princess Azula's firebending training.
Lo and Li were both appointed as Azula's firebending mentors when she was a child.
During 100 ASC, they accompanied the Fire Nation Princess on her journey to the Earth Kingdom to retrieve Prince Zuko. When the Prince had escaped, Lo and Li advised Azula to abandon the Royal Procession in favor of a smaller elite group to better increase her chances of capturing her fugitive brother and uncle.
The duo later presided over a rally held at the Fire Nation Capital's Royal Plaza, where they boastfully declared victory over the Earth Kingdom due to the efforts of Azula and the newly returned Prince Zuko.
Later, Zuko, Mai, Ty Lee, and Azula stayed with the sisters on Ember Island where they owned a small but comfortable beach house. Lo and Li had been coming to this tiny beach cottage since they were infants, and once their parents died, they inherited the cottage. When life in the Fire Nation Capital became too hectic, the twins escaped to their little oasis in order to relax.
While sharing a meal with the teenagers, the sisters mentioned that the beach had special "powers" and that it supposedly changed people, smoothing even the roughest edges. After sharing this wisdom, they clapped their hands and announced that they were going to the beach, removing their outer garments, much to the displeasure of the others.
In light of Azula's frantic purging of the Royal Palacestaff, Lo and Li expressed their concern for Azula's welfare and suggested to postpone her coronation. However, the Princess misinterpreted their remark as having lack of faith in her abilities to rule, and consequently ordered the twins to fight an Agni Kai. Upon remarking that they were not firebenders, Azula promptly banished Lo. However, since the Princess pointed at Li while giving the order, the twin sisters were left in confusion as to who was banished and who was allowed to remain at the palace.